Prepare the Crust:Preheat your oven to 325°F (165°C). Line a 9×13-inch baking pan with parchment paper, leaving an overhang for easy removal. Combine the graham cracker crumbs and melted butter in a medium bowl, then press the mixture evenly into the bottom of the pan to form a compact crust.
Make the Cheesecake Filling:In a large mixing bowl, beat the softened cream cheese and granulated sugar with an electric mixer until smooth and creamy. Add the vanilla extract and mix until incorporated. Add the eggs one at a time, beating just until combined after each addition. Finally, mix in the sour cream until the filling is smooth.
Assemble the Bars:Pour the cream cheese filling over the prepared crust and spread it evenly. Dollop cherry pie filling over the cheesecake layer and use a knife to gently swirl it into the filling to create a marbled effect. Sprinkle the chopped pistachios evenly over the top.
Bake and Cool:Bake the cheesecake bars in the preheated oven for 40–45 minutes, or until the cheesecake is set and slightly golden around the edges. Allow the bars to cool to room temperature, then refrigerate for at least 2 hours to firm up before slicing.
Slice and Serve:Use the parchment overhang to lift the bars from the pan. Slice into squares or rectangles and serve chilled.